Monday, April 30, 2012

Drug Discovery for Autism seems more Prospective

After conducted research, researchers hope the drug they found could be used to cure autism in humans. United State National Institutes of Health examined the use of drugs GRN-529 to reduce the common symptoms that are often occur in autism people. The drug may help brain cells to communicate each other.

Although it had been circulating that autism can not be cured by medication, researchers believe that the use of these drugs can reduce the symptoms of autism. The medication is try to make brain cells communicate at synapses (the gaps between human brain cells).

The test was performed on rats with autism. Autistic mice lack in socialization and communication with other mice. They also spend a lot of time to perform repeated activities.

Once injected, the rats showed a better behavior. Such as reducing repetitive activity and demonstrate  improvement in social level. The researchers believe these findings enhance the chances of the drug can be used in treatment of autism.

"Because of high cost, both in money and emotional to families, schools and health care system, we hope the research can meet the needs of drugs that address the underlying symptoms," said Dr. Jacqueline Crawley, one of the researchers from National Institute of Mental Health.

Uta Frith, professor of cognitive development from University College London said: "The processes at synapses has long been suspected as the cause of autism."

The study, published in journal Science Translational Medicine is even showing positive symptoms in mice, not simply be applied to humans. It took a long time and a series of further research to test its feasibility in humans.

Autistic behaviors known to affect 1 percent of  children. The scale varies from mild to severe. Symptoms range from social constraints, language barriers, and like to repeat movement. So far, people with autism treated through special education such as speech and behavioral therapy.

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